Paper and board. Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2) Ingestion-build-100998 BS ISO 20474 brings an

BS ISO 20474 brings an internationally consistent approach to safety

Such pressure differences may be caused by changes in temperature and will result in the enclosure "breathing" but will not cause a significant flow of explosive atmosphere into or through the enclosure

technological properties

due to their size

Definitions from ODP standards refined or extended in this Recommendation | International Standard

Paper and board. Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2) Ingestion-build-100998 BS ISO 20474 brings an1 Scope This European Standard specifies a test method for the laboratory assessment of the potential cytotoxic effect of paper and board intended to come into contact with foodstuffs using specifically the HepG2 cell line. Compared to the EN 15845[1], HepG2 cells are more representative of a human oral exposure to xenobiotics, due to the presence in the cells of phase I, II and III enzymes of the metabolism.