The Binding of Isaac: Four Souls STRATEGY and both LTPK Sets may

and both LTPK Sets may be used together in any order

and they secretly select a word from a set given in a deck of cards

2-6 players start the game by choosing (in reverse player order) a starting location for one of their three city pieces

Being cursed forces a player to take the Cursed card and roll the black die along with the rest of his dice pool

Multiple expansions are available for Hero Realms that allow players to start as a particular character (Cleric

The Binding of Isaac: Four Souls STRATEGY and both LTPK Sets mayThe official Binding of Isaac multiplayer card game, about sacrifice, betrayal and hoarding. 2 4 players take turns playing loot cards and using items to kill monsters that yield more items, loot, and sometimes souls. The first player to end their turn with 4 souls is the winner. Cooperation, barter, and betrayal is encouraged.